Always at night
Retinol is most effective applied at night, before you moisturize.
BEFORE & AFTER




Third party lab consumer panel test. Individual results may vary
Minimizes the appearance of fine lines and wrinkles, and the look of skin roughness.
Minimizes the look of dark spots and discoloration, and helps visibly even skin tone.
Hyaluronic acid hydrates and visibly plumps overnight, for a softer, smoother-looking appearance.
Approved product claim: 2.5% Bio-Retinol + Retinol minimizes fine lines, wrinkles, dark spots and discoloration and promotes smooth, radiant skin.
The retinol is encapsulated in evening primrose. Encapsulation protects retinol's stability, which is the difference between a serum that still works at the end of the bottle and one that does not.
2.5% Bio-Retinol + Retinol Complex™, working together on the look of fine lines and wrinkles.
Jojoba, shea and murumuru butters, hyaluronic acid, vitamin E and panthenol are in the formula alongside the retinol, not sold separately as the thing that repairs the damage.
SuperJuice Complex™ replaces conventional filler water with organic grape, apple, aloe and lemon juices, so the base is nutrient-dense from the first drop. Over 2,000 ingredients are excluded by design.
START HERE
Most people who give up on retinol started too fast. Tell us where your skin is and we will give you a schedule.
Apply at night to face, neck and décolleté, before your moisturizer. Broad spectrum SPF every morning.
Apply at night to face, neck and décolleté, before your moisturizer. Broad spectrum SPF every morning.
Apply at night to face, neck and décolleté, before your moisturizer. Broad spectrum SPF every morning.
Retinol is most effective applied at night, before you moisturize.
Wear a broad spectrum sunscreen every morning while you are using retinol. This is not optional.
Make sure your skin is well hydrated, especially when you are starting out.
If your skin is reacting, drop back a step rather than pushing through. Some people stay at once or twice a week and are happy there.
THE PM ROUTINE
STEM CELLULAR 2-in-1 Cleanser. Lather in wet palms, massage into damp skin for at least a minute, rinse and pat dry.
Anti-Wrinkle Retinol Overnight Serum. Apply at night to face, neck and décolleté, building up as tolerated.
SleepWrinkle Retinol Overnight Eye Cream. Massage around the entire eye from the inner corner, then pat in the excess.
Anti-Wrinkle Ceramide Overnight Cream. Seals in the moisture. No retinol in this one, it is the moisture step.


STEM CELLULAR™
2.5% Bio-Retinol + Retinol for the eye area. $45
97% showed improvement in appearance of eye area fine lines and wrinkles*
STEM CELLULAR™
The moisture-seal step. No retinol.
91% improved moisture replenishment overnight†
EVERY MORNING
Broad spectrum mineral SPF 45. Retinol at night only works if you protect in the morning. $39.50
*Digital image instrument analysis on the SleepWrinkle Retinol Overnight Eye Cream. Independent 4 week lab analysis. Individual results may vary. †3rd party lab, after 5 weeks, on the Anti-Wrinkle Ceramide Overnight Cream. Individual results may vary. Both claims belong to those products and must never be attached to this serum.
Once or twice a week to begin with, at night, on clean dry skin. Build to every other night, then nightly, only as your skin tolerates it. If you get dryness or irritation, drop back a step rather than pushing through. Wear a broad spectrum sunscreen every morning while you are using it.
Face, neck and décolleté, at night, before your moisturizer. The neck and décolleté are the parts most people skip.
It is a 2.5% Bio-Retinol + Retinol Complex™, with the retinol encapsulated in evening primrose to protect its stability. Encapsulation matters as much as the number on the front: an unstable retinol degrades in the bottle, so what is on the
label is not what reaches your skin.
Talk to your doctor before using any retinol product if you are pregnant, planning to be, or breastfeeding. We are not able to advise on this for you.
Use vitamin C in the morning and this at night rather than layering them together. Gentle exfoliation can help absorption, but do not exfoliate on the same night you apply retinol while you are still building up.
A fresh citrus scent from the fruit extracts and essential oils in the formula, not added perfume. The ingredient list flags d-limonene, linalool and geraniol as potential allergens, which occur naturally in those oils.
30 mL / 1 fl oz. Because you build up slowly and use a small amount, most people get several months out of a bottle, longer if you are still at once or twice a week.
*certified organic · † plant derived
Aloe barbadensis leaf juice*, glycerin†, simmondsia chinensis (jojoba) seed oil*, coconut alkanes†, glyceryl stearate†, stearic acid†, pyrus malus (apple) juice*, vitis vinifera (grape) juice*, helianthus annuus (sunflower) seed oil*, glyceryl stearate citrate†, cetyl alcohol†, stearyl alcohol†, caprylyl glycol†, oenothera biennis (evening primrose) leaf cell extract / [retinol/soybean]†, butyrospermum parkii (shea) butter*, gossypium herbaceum (cotton) seed oil†, linum usitatissimum (linseed) oil†, bidens pilosa extract†, astrocaryum murumuru seed butter†, sodium hyaluronate (hyaluronic acid)†, ubiquinone (CoQ 10), tocopherol (Vitamin E)†, panthenol (Vitamin B5), magnesium ascorbyl phosphate (Vitamin C), coco-caprylate/caprate†, malus domestica (apple) fruit cell culture extract†, vitis vinifera (grape) fruit cell extract†, citrus limon (lemon) fruit extract†, camellia sinensis (green tea) extract*, acetyl hexapeptide-8, xanthan gum, mica, allantoin, titanium dioxide (CI 77891), ethylhexylglycerin, diheptyl succinate†, polyglyceryl-6 distearate†, capryloyl glycerin/sebacic acid copolymer†, thioctic acid (alpha lipoic), litsea cubeba oil†, cinnamomum camphora linalooliferum oil†. Potential allergens: d-limonene†, linalool†, geraniol†